Comparison of Pharmacodynamics and Adverse effects of drug between Pediatric and Geriatric Group

Pharmacodynamics in infant: 


Pharmacodynamics in adults:

Pharmacodynamics in adults change with age including receptor alterations, impaired signal transduction and decreased homeostatic regulation.

Adverse Effects in infants:

Adverse Effects in adults:


Incidence of Adverse effects reactions increases by age as elderly receive more medicines.
For patients > 50 years:
a) Adverse effects reactions are 5% of occurrence for 1-2 given medicines.
b) Adverse effects reactions increase to 20% of occurrence for more than 5 given medicines.

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